Brain atrophy and white matter hyperintensities are independently associated with plasma neurofilament light chain in an Asian cohort of cognitively impaired patients with concomitant cerebral small vessel disease

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

Plasma NfL has potential utility in stratifying individual and combined contributions of AD pathology and CSVD to cognitive impairment.

Authors: Joyce R. Chong, Saima Hilal, Nicholas J. Ashton, Thomas K. Karikari, Anthonin Reilhac, Henri A. Vrooman, Michael Schöll, Henrik Zetterberg, Kaj Blennow, Christopher Chen, Mitchell K.P. Lai

DOI: https://doi.org/10.1002/dad2.12396

Publish Year: 2023