Researcher Collab

Clarity AD: Asian regional analysis of a phase III trial of lecanemab in early Alzheimer's disease

The Journal of Prevention of Alzheimer s Disease

In the Clarity AD Asian region cohort, the overall efficacy, biomarker changes and safety profile of lecanemab were consistent with the overall population, with a favorable risk-benefit profile and manageable risks. ARIA events and infusion-related reactions occurred less commonly with lecanemab in the Asian region subgroup than the overall population.

Authors: Christopher Chen, Sadao Katayama, Jae Hong Lee, Juneyoung Lee, Masaki Nakagawa, Kentaro Torii, Tomoo Ogawa, Amitabh Dash, Michael C. Irizarry, Shobha Dhadda, Michio Kanekiyo, Steve Hersch, Takeshi Iwatsubo

DOI: https://doi.org/10.1016/j.tjpad.2025.100160

Publish Year: 2025