Bioactive compounds and other plant constituents have been shown to vary across cultivation regions, species, environmental conditions, and extraction methods, among other factors. Picrorhiza kurroa is a wonderful medicinal plant, a member of the Plantaginaceae family, indigenous to the upper Himalayan region of India. The present research aimed to screen for phytochemicals and characterize the ethanolic rhizome extracts of P. kurroa collected from Uttarakhand, India. Rhizome extract obtained using the Soxhlet apparatus with ethanol, then preconcentrated in a vacuum rotary evaporator. The extracts were characterized using a Fourier transform infrared spectrometer (FTIR) and Gas chromatography-mass spectrometry (GC-MS) to identify key functional groups and phytoconstituents. FTIR spectra showed the signature absorption bands of functional groups, including alkyl halides, vinyl groups, primary amines, phenols, alcohols, and nitro compounds. GC-MS analysis identified 47 phytoconstituents in the extracts. The extract exhibited significant antibacterial and antifungal activities. The findings suggest that P. kurroa will facilitate the development of herbal medicines, potentially leading to the discovery of new therapeutic agents.
Authors: 1Bhumika Varshney Department of Biotechnology, Mangalayatan University, Beswan, Aligarh 2Dr. Soni Singh Department of Biotechnology, Mangalayatan University, Beswan, Aligarh 3Dr. Amarjeet Singh Department of Pharmacy.Innovative College of Pharmacy
Publish Year: 2025
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