PhD candidate at UCL specialising in ischaemia–reperfusion injury, with a focus on haemorrhagic shock, cardiac arrest, and post-resuscitation care and prognostication. My research centres on identifying and evaluating protective strategies to mitigate reperfusion injury using well-established pre-clinical models.
Ischaemia–reperfusion injury: pathophysiology prognostication and therapeutic strategies Cardiac arrest and resuscitation science Haemorrhagic shock and global ischaemia models Tissue perfusion and oxygenation monitoring Mitochondrial physiology and therapeutic targeting
Early HTC showed no neurologic nor survival benefit in cardiac arrest survivors. Nasal evaporative cooling during CPR may benefit those with shockable rhythms. Delays in reaching the target temperature may underlie the failure of HTC. Future studies should evaluate whether achieving target temperature, for example, within 30 minutes, rapidly improves outcomes.
Nitazene-related deaths have increased in England, Wales, and Northern Ireland, and may have been underestimated due to post-mortem instability. Urgent public health action is required to reduce nitazene-related harms.
Outcomes following cardiac arrest remain universally poor, and early identification of patients at risk of poor recovery is essential to gu…